[SQU] improving performance by acls?

Hi folks,

I am thinking why can i try to improve the performance of squid by some acls.
ie I am trying to do the some functionalities, which L7 switches normally do with Squid.
By using URLs we can identify whether requested objects are cachable or not. If not, requests can be passed to origin server by always_direct Directive in squid.conf.

Note:
        I am using Transparent caching.

Am i in the right direction?
If so, How much (%) we can improve ?

Thanks,
Venkatesh.

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